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Three people were taken to hospitals after a crash on North Main Street Wednesday afternoon.

The crash at the intersection of North Main Street and Holly Lawn Parkway happened at 12:15 p.m., according to a city press release.

The accident involved a GMC Arcadia pick-up that had flipped onto the driver’s side, and a Jeep Cherokee.

Suffolk Fire & Rescue crews responded and provided emergency medical assessment and treatment. The adult female driver and a juvenile had to be extricated through the windshield from the pick-up, and both were transported to a local hospital with injuries not considered life-threatening, the release stated.

The adult male driver of the Jeep was also transported to a local hospital with what were later determined to be life-threatening injuries.

A portion of the roadway was closed immediately following the accident for approximately an hour until all vehicles could be removed from the roadway.

The cause of the accident remains under investigation.