Firefighters rescued a husband and wife from their burning home in the Lee-Jackson neighborhood downtown on Saturday.

Suffolk Fire and Rescue responded at 4:35 a.m. to a call reporting smoke in the neighborhood, according to city spokeswoman Diana Klink. When firefighters arrived, they found a home in the 400 block of Wilson Street with heavy smoke and flames extending from the first floor to the second story at the rear of the house.

Once firefighters entered the home and knocked down the flames, they found the couple in the downstairs bedroom and were able to pull them to safety, Klink stated in a press release. A dog that was chained to the front porch also was rescued.

Additional fire units responded to the scene, including Engines 1, 2 and 3; Ladder 3; Medics 3 and 6; Battalion 1; and Rescue 1.

No firefighters were injured while battling the blaze, and the residents of the home refused medical treatment, Klink stated.

The home sustained heavy damage, and the Suffolk chapter of the American Red Cross is assisting the couple, who were renting the home.

The Suffolk Fire Marshall’s office is investigating the cause of the fire.